Modeling nutrient consumptions in large flow-through bioreactors for tissue engineering

Bioreactors in tissue engineering.

A bioreactor can be defined as a device that uses mechanical means to influence biological processes. In tissue engineering bioreactors can be used to aid in the in vitro development of new tissue by providing biochemical and physical regulatory signals to cells and encouraging them to undergo differentiation and/or to produce extracellular matrix prior to in vivo implantation. This chapter dis...

Bioreactors for Liver Tissue Engineering

A cute liver failure (ALF) patients have a high risk of mortality. The elective treatment for ALF still is orthotopic liver transplantation. Donor organ scarcity and the associated high costs make transplantation possible for only about one third of the patients on the transplantation waiting list. Engineering a biological liver substitute is an interesting alternative to the traditional ALF th...

IV.3. Bioreactors in tissue engineering.

The Role of Bioreactors in Tissue Engineering for Musculoskeletal Applications

Tissue engineering involves using the principles of biology, chemistry and engineering to design a 'neotissue' that augments a malfunctioning in vivo tissue. The main requirements for functional engineered tissue include reparative cellular components that proliferate on a biocompatible scaffold grown within a bioreactor that provides specific biochemical and physical signals to regulate cell d...

A ComputerProgram for Modeling Large Deformation Nonlinear and Transient problems in Geotechnical Engineering

CA2 (Continuum Analysis, 2- dimensional) is a computer program developed by the author. CA2 can solve a variety of complex geotechnical problems using explicit finite difference method. In this paper, an introduction will be given to the theoretical and numerical basis of the program and the capability of the code will be shown by solving a few interesting nonlinear and transient problems. Fina...